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Zepbound vs Rybelsus: cost in Canada

Zepbound and Rybelsus side by side: prices and listings only, not how the medications work.

Last checked 2026-11-12

Zepbound and Rybelsus side by side

Fact	Zepbound	Rybelsus
Generic name	tirzepatide	semaglutide
Form	Injection	Tablet
Maker	Eli Lilly Canada Inc.	Novo Nordisk Canada Inc.
Doses sold in Canada	2.5 mg · 5 mg · 7.5 mg · 10 mg · 12.5 mg · 15 mg	1.5 mg · 3 mg · 4 mg · 7 mg · 9 mg · 14 mg
Lowest public price	$299.44 · Cloudcure	$290 · Cloudcure
The lowest price is for	2.5 mg: 1 pen (4 doses)	Any dose: 30 tablets
Median starting price	$362.02	$318.50
Highest starting price	$849.95	$324.99
Providers with a price	10	8
Public plans that list it	0 of 14	7 of 14
Savings program of the maker	myzepbound Savings & Support Program	Rybelsus Retail Card Program, Novo Nordisk Care, Novo Nordisk Care Rx
Generic on the market	No product with the status Marketed	2 products with the status Marketed

A starting price is the lowest public price that one provider shows for one medication, for any dose. The lowest, the median and the highest price of a medication come from the starting prices of its providers.

A public plan counts when a source that we confirmed shows the medication on its list, as a regular benefit or with conditions. The generics are the products of the same molecule in the Drug Product Database of Health Canada.

Zepbound and Rybelsus: questions

Which costs less, Zepbound or Rybelsus?

Rybelsus has the lower starting price. The lowest public Rybelsus price is $290, at Cloudcure (Any dose: 30 tablets). The lowest public Zepbound price is $299.44, at Cloudcure (2.5 mg: 1 pen (4 doses)). We checked the two prices on 2026-11-12. The two prices can be for different doses and packs. Open each price list to compare one dose.

Do public drug plans list Zepbound and Rybelsus?

None of the 14 public drug plans lists Zepbound in a source that we confirmed. 7 of 14 public drug plans list Rybelsus in a source that we confirmed. A plan can list a medication with conditions, and the plan decides each request. The coverage checker shows what each plan says.

Is a generic tirzepatide or a generic semaglutide on the market in Canada?

The Drug Product Database of Health Canada shows no generic tirzepatide product with the status Marketed. The Drug Product Database of Health Canada shows 2 generic semaglutide products with the status Marketed. The generic tracker shows each product and its status.

More comparisons

See every Zepbound price

See every Rybelsus price